The distinction between this entity and other endometrial tumors is important especially for treatment and prognosis. D Tumor cells large and pleomorphic, with moderate amount of granular cytoplasm and vesicular nuclei, resembling hepatic cells. After the AFP level decreased to a normal range, all the patients were evaluated with diagnostic imaging, such as magnetic resonance imagining MRI and computed tomography CT , and examination under anesthesia. Our findings confirmed that recurrence must be expected in approximately every third patient with nonmetastatic RMS. Two cases of EST of the vagina in infants aged 9 and 17 months are reported. Introduction Germ cell tumors GCT are relatively uncommon childhood tumors. We emphasize primary chemotherapy with close follow-up of the patient as the treatment of choice to allow preservation of sexual function.
Conservative management of primary vaginal endodermal sinus tumor and rhabdomyosarcoma
Support Center Support Center. In the s, there was a gradual shift toward more conservative surgeries, such as local excision, polypectomy, or cervical conization with or without chemotherapy [ 31 , 32 ]. Successful treatment of an endodermal sinus tumor of the vagina by chemotherapy alone: a rare case of an infant diagnosed by pathological examination of discharged tumor fragment. Various histopathological subtypes of EST include reticular microcystic , macrocystic, endodermal sinus type, papillary, solid, glandular, myxomatous, sarcomatoid, polyvesicular, hepatoid and parietal types. Long-term irradiation has secondary effects of sterility, aseptic necrosis of the femoral head, and abnormal growth of the pelvic bones.
Vaginal endodermal sinus tumor. | latinsayings.info
Patients typically present with vaginal bleeding, with or without a polypoid mass protruding from the vagina [ 12 , 13 ]. Approximately half of all RMS cases in the genital tract arise in the vagina and most commonly in the first decade of life, while its less common cervical counterpart most commonly occurs in the second and third decades of life [ 8 , 23 , 24 ]. The second case showed the presence of Schiller Duval bodies and intra and extracellular hyaline globules which were Periodic-acid Schiff PAS positive . Alpha-fetoprotein-producing non-germ cell tumours of the female genital tract. Conservative treatment for girls with nonmetastatic rhabdomyosarcoma of the genital tract: a report from the Study Committee of the International Society of Pediatric Oncology. Cancer ; The diagnosis is based on histological pattern, characteristic Schiller-Duval bodies, PAS stain positive diastase resistant hyaline globules and raised serum alpha-fetoprotein AFP.
Published online Jun 3. Rhabdomyosarcoma of the cervix in sisters with review of the literature. Immunohistochemical differentiation of clear-cell carcinoma of the female genital tract and endodermal sinus tumor with the use of alpha-fetoprotein and Leu-M1. The vagina is an extremely rare site for germ cell tumors GCT. Further large-scale studies with long-term follow-up are needed to confirm our results and to define the best treatment protocols for these malignancies. After the AFP level decreased to a normal range, all the patients were evaluated with diagnostic imaging, such as magnetic resonance imagining MRI and computed tomography CT , and examination under anesthesia.
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